Across cardiovascular clinics worldwide, physicians frequently encounter a recurring narrative: patients who, despite adhering to prescribed therapies, remain burdened by breathlessness and persistent chest discomfort during routine activities. These are not outliers or critical emergencies but rather a growing cohort of individuals living with chronic, stable angina, often confronting limited treatment options outside of invasive procedures. It was in response to this widespread therapeutic gap that the Multicenter Study of Enhanced External Counterpulsation (MUST-EECP) was conceived. This pivotal trial aimed to evaluate whether a non-invasive intervention, such as EECP, could deliver measurable improvements in exercise-induced myocardial ischemia and reduce the frequency of anginal episodes, ultimately pointing toward a more patient-centric paradigm in cardiac care. Purpose and Scope of the MUST-EECP Study The MUST-EECP study was a rigorously designed, multicenter, randomized...
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